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Keqiang Chen Selected Research

GTP-Binding Proteins (G-Protein)

1/2021Leukocyte chemotactic receptor Fpr1 protects against aging-related posterior subcapsular cataract formation.
10/2020The G-protein-coupled chemoattractant receptor Fpr2 exacerbates neuroglial dysfunction and angiogenesis in diabetic retinopathy.
1/2020The G-Protein Coupled Formyl Peptide Receptors and Their Role in the Progression of Digestive Tract Cancer.
2/2016Formylpeptide receptor 1 mediates the tumorigenicity of human hepatocellular carcinoma cells.
1/2016The G-protein coupled chemoattractant receptor FPR2 promotes malignant phenotype of human colon cancer cells.
12/2011Chemoattractant receptors as pharmacological targets for elimination of glioma stem-like cells.
9/2011Annexin 1 released by necrotic human glioblastoma cells stimulates tumor cell growth through the formyl peptide receptor 1.
8/2009Synergy of TRIF-dependent TLR3 and MyD88-dependent TLR7 in up-regulating expression of mouse FPR2, a promiscuous G-protein-coupled receptor, in microglial cells.
2/2009Regulation of the leucocyte chemoattractant receptor FPR in glioblastoma cells by cell differentiation.
6/2008Cooperation between NOD2 and Toll-like receptor 2 ligands in the up-regulation of mouse mFPR2, a G-protein-coupled Abeta42 peptide receptor, in microglial cells.
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Keqiang Chen Research Topics

Disease

25Neoplasms (Cancer)
03/2022 - 08/2005
20Inflammation (Inflammations)
01/2021 - 02/2006
10Carcinogenesis
01/2022 - 06/2007
8Glioblastoma (Glioblastoma Multiforme)
09/2019 - 04/2006
7Muscle Cramp (Cramp)
01/2021 - 06/2013
7Alzheimer Disease (Alzheimer's Disease)
08/2009 - 11/2005
6Neoplasm Metastasis (Metastasis)
01/2021 - 05/2008
6Glioma (Gliomas)
11/2012 - 04/2006
5Infections
03/2022 - 10/2007
4Colitis
11/2020 - 10/2016
2Bacterial Infections (Bacterial Infection)
01/2021 - 02/2006
2Fatty Liver
04/2017 - 03/2016
2Neurodegenerative Diseases (Neurodegenerative Disease)
01/2017 - 02/2006
1Communicable Diseases (Infectious Diseases)
03/2022
1Lung Abscess
03/2022
1Partial Epilepsies (Epilepsy, Partial)
01/2022
1Cataract (Cataracts)
01/2021
1Rupture
01/2021
1Eye Infections
01/2021
1Diabetic Retinopathy (Retinopathy, Diabetic)
10/2020
1Stomach Neoplasms (Stomach Cancer)
01/2019
1Body Weight (Weight, Body)
01/2019
1Pulmonary Fibrosis (Fibrosing Alveolitis)
01/2018
1Dysbiosis
01/2018
1Lung Neoplasms (Lung Cancer)
12/2017
1Type 2 Diabetes Mellitus (MODY)
12/2017
1Septic Shock (Toxic Shock Syndrome)
10/2017
1Atherosclerosis
04/2017
1Atherosclerotic Plaque (Atheroma)
04/2017
1Protein Deficiency
01/2017
1Non-alcoholic Fatty Liver Disease
03/2016
1Liver Neoplasms (Liver Cancer)
02/2016
1Hepatocellular Carcinoma (Hepatoma)
02/2016
1Colonic Neoplasms (Colon Cancer)
01/2016
1Sepsis (Septicemia)
04/2015
1Chronic Disease (Chronic Diseases)
03/2015
1Lung Injury
01/2014
1Wounds and Injuries (Trauma)
01/2014

Drug/Important Bio-Agent (IBA)

15Formyl Peptide Receptors (Formyl Peptide Receptor)IBA
01/2021 - 11/2005
14GTP-Binding Proteins (G-Protein)IBA
01/2021 - 12/2005
13Peptides (Polypeptides)IBA
11/2020 - 12/2005
10Chemotactic FactorsIBA
01/2020 - 02/2006
8Proteins (Proteins, Gene)FDA Link
12/2017 - 04/2006
6CathelicidinsIBA
01/2021 - 06/2014
6LigandsIBA
01/2016 - 08/2009
6Amyloid beta-PeptidesIBA
08/2009 - 12/2005
4Antimicrobial PeptidesIBA
01/2021 - 01/2018
4ChemokinesIBA
04/2018 - 01/2013
3Anti-Bacterial Agents (Antibiotics)IBA
03/2022 - 01/2018
3EndotoxinsIBA
03/2016 - 03/2015
3G-Protein-Coupled Receptors (Receptors, G Protein Coupled)IBA
11/2012 - 04/2006
3Epidermal Growth Factor (EGF)IBA
08/2008 - 06/2007
2Biomarkers (Surrogate Marker)IBA
01/2022 - 01/2021
2Dextran SulfateIBA
01/2018 - 04/2013
2AzoxymethaneIBA
01/2018 - 04/2013
2ErbB Receptors (EGF Receptor)IBA
12/2017 - 06/2007
2Pathogen-Associated Molecular Pattern MoleculesIBA
12/2017 - 10/2011
2Apolipoproteins E (ApoE)IBA
04/2017 - 01/2017
2ApolipoproteinsIBA
04/2017 - 03/2016
2CollagenIBA
04/2017 - 02/2006
2CalciumIBA
02/2016 - 09/2007
2Chemokine CCL2 (Monocyte Chemoattractant Protein 1)IBA
01/2014 - 01/2013
2Messenger RNA (mRNA)IBA
01/2014 - 01/2013
2AnnexinsIBA
11/2012 - 09/2011
2Toll-Like Receptors (Toll-Like Receptor)IBA
10/2011 - 10/2007
2AgarIBA
09/2011 - 02/2009
2Tyrosine (L-Tyrosine)FDA Link
08/2008 - 06/2007
2Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA
08/2008 - 09/2007
2Lipoxygenase InhibitorsIBA
09/2007 - 04/2006
2nordyIBA
09/2007 - 04/2006
2N-Formylmethionine Leucyl-PhenylalanineIBA
06/2007 - 04/2006
1Serine Proteases (Serine Protease)IBA
01/2022
1Levetiracetam (Keppra)FDA LinkGeneric
01/2022
1Oxcarbazepine (Trileptal)FDA LinkGeneric
01/2022
1TrypsinIBA
01/2022
1MucinsIBA
01/2021
1LipopolysaccharidesIBA
01/2021
1Peptide Hydrolases (Proteases)FDA Link
01/2021
1Glucose (Dextrose)FDA LinkGeneric
09/2019
1Growth Factor ReceptorsIBA
09/2019
1Transcription Factors (Transcription Factor)IBA
01/2019
1sodium sulfate (sodium bisulfate)FDA LinkGeneric
01/2019
1Dextrans (Dextran)FDA Link
01/2019
1Pharmaceutical PreparationsIBA
01/2019
1MetallothioneinIBA
01/2019
1Bleomycin (Blenoxane)FDA LinkGeneric
01/2018
1Tyrosine Kinase InhibitorsIBA
12/2017
1Erlotinib Hydrochloride (CP 358,774)FDA Link
12/2017
1Metformin (Glucophage)FDA LinkGeneric
12/2017
1Niacin (Nicotinic Acid)FDA LinkGeneric
10/2017
1LipidsIBA
04/2017
1ursodoxicoltaurineIBA
10/2016
1Interleukin-8 (Interleukin 8)IBA
02/2016
1CCR2 ReceptorsIBA
06/2013
1Chemokine ReceptorsIBA
06/2013
1AntigensIBA
01/2013

Therapy/Procedure

4Therapeutics
12/2017 - 12/2011
1Punctures
04/2015
1Ligation
04/2015
1Transplantation
01/2013